The Connelly Laboratory at the University of Virginia has an immediate opening for molecular biologist with expertise in peptide hormone assay in a Senior Scientist role. Join our team to be help build powerful translational models of epigenetic change in response to early environment, for applications ranging from model system development to human behavioral and neural prediction and intervention.
We invite applications from researchers with training in hormone receptor measurement and manipulation, biomarker development, and model system neuroscience approaches to lead an arm of a translational neuroscience project focusing on measurement and manipulation of neurohypophyseal peptides and their receptors. The researcher will have the opportunity to collaborate closely with colleagues in the nearby School of Education, School of Medicine and School of Engineering, to initiate work with modeling changes in neurohypophyseal peptides and their receptors in response to early environmental change. In addition, the researcher will take on a senior role in the laboratory. They will help train graduate and undergraduate students in common molecular biological bench skills and animal maintenance and surgical techniques, assist lab members with molecular assays for measurement of the oxytocin system and DNA and RNA analysis for ongoing projects when needed. The scientist will administer relevant regulatory protocols for animal and biosafety work, maintain detailed scientific records of their work, and help keep laboratory safety standards. They will have the opportunity to write high quality scientific papers, aid in drafting grant proposals, and present their results at national or international conferences.
The Connelly Lab performs cutting-edge research in translational neuroepigenetics. We are particularly interested in the use of the DNA methylation state of genes as markers for neural development, behavior and disorder, and genomewide methods to identify transcriptome changes in response to early experience. The laboratory is well funded, dynamic, collaborative, and collegial. Learn more at www.connellylab.com.
The historic University of Virginia is consistently ranked one of the top 3 public universities in the country by US News and World Report, with a vibrant research enterprise that support cross-disciplinary scholarship. We are located in beautiful Charlottesville, VA, near the Blue Ridge mountains, with a strong cultural and restaurant scene and college town energy. Travel to Washington, DC in just two hours, or the Atlantic ocean in three.
QUALIFICATIONS: Completion of Ph.D. in Biomedical Science or a related discipline with an emphasis in peptide assay development and a minimum of 5 years hands-on postdoctoral training experience in a neurohypophyseal peptide laboratory. Experience in development and analysis of ELISA and other molecular and cellular assays is desired. A record of high quality research as demonstrated by publications in top tier journals and external presentations is required. A deep mechanistic understanding of the cellular/molecular pathways is highly desired. Previous experience with handling and breeding rats, mice and prairie voles, and use of surgical techniques such as: stereotaxic, iv & icv cannulation, adrenalectomy, vagotomy, laparotomy, dissection of central/peripheral tissues in rodents is a plus. Strong team management skills, ability to work with minimal supervision in a collaborative framework and demonstrated eagerness to learn new techniques and skills is required. Required technical skills: basic molecular biology, experience in assaying oxytocin peptide in human and animal samples, RNA quantitation using single gene techniques, and cell culture.
APPLICATION PROCEDURE: Apply online at https://uva.wd1.myworkdayjobs.com/ and attach the following items as a single complied PDF in the “Resume” field.
- A cover letter that explains why you are interested in joining the Connelly lab in this unique position, how the position fits into your career goals, and a brief summary of your relevant research experience (max. 2 pages).
- Curriculum vitae
- Contact information for three (3) references if not already included in the CV. Listing them here represents permission to contact them unless you specify otherwise in your cover letter.
APPLICATION DEADLINE: Review of applications will begin on August 8, 2022, and the position will remain open until filled. The University will perform background checks on all new hires prior to employment.
This is a one-year appointment that may be renewed contingent upon available funding and satisfactory performance.
For more information on the benefits available to research scientists at UVA, visit and hr.virginia.edu/benefits.
COVID Vaccination Requirement and Guidelines
Please visit the UVA COVID-19 Job Requirements and Guidelines webpage prior to applying for current information regarding vaccination requirements and guidelines for employment at UVA.
The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person’s perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.